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DNA topoisomerases from pathogenic fungi: targets for the discovery of antifungal drugs.

DNA topoisomerases, a class of enzymes that change the topological structure of DNA, have been shown to be the target of many therapeutic agents, including antibacterial agents (quinolones) and anticancer agents. These drugs inhibit the enzyme in a unique way so that the enzyme is converted into a c...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Principais autores: Shen, L L, Baranowski, J, Fostel, J, Montgomery, D A, Lartey, P A
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1992
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2778
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