DNA topoisomerases from pathogenic fungi: targets for the discovery of antifungal drugs.

DNA topoisomerases, a class of enzymes that change the topological structure of DNA, have been shown to be the target of many therapeutic agents, including antibacterial agents (quinolones) and anticancer agents. These drugs inhibit the enzyme in a unique way so that the enzyme is converted into a c...

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Bibliographic Details
Main Authors:	Shen, L L, Baranowski, J, Fostel, J, Montgomery, D A, Lartey, P A
Format:	Artigo
Language:	Inglês
Published:	1992
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC245544/ https://ncbi.nlm.nih.gov/pubmed/1336349
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DNA topoisomerases from pathogenic fungi: targets for the discovery of antifungal drugs.

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