DNA topoisomerases from pathogenic fungi: targets for the discovery of antifungal drugs.
DNA topoisomerases, a class of enzymes that change the topological structure of DNA, have been shown to be the target of many therapeutic agents, including antibacterial agents (quinolones) and anticancer agents. These drugs inhibit the enzyme in a unique way so that the enzyme is converted into a c...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336349/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2778 |
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