DNA topoisomerases from pathogenic fungi: targets for the discovery of antifungal drugs.

DNA topoisomerases, a class of enzymes that change the topological structure of DNA, have been shown to be the target of many therapeutic agents, including antibacterial agents (quinolones) and anticancer agents. These drugs inhibit the enzyme in a unique way so that the enzyme is converted into a c...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Shen, L L, Baranowski, J, Fostel, J, Montgomery, D A, Lartey, P A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336349/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2778
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