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A Human Estrogen Receptor (ER)α Mutation with Differential Responsiveness to Nonsteroidal Ligands: Novel Approaches for Studying Mechanism of ER Action

Estrogens, acting through the estrogen receptors (ERs), play crucial roles in regulating the function of reproductive and other systems under physiological and pathological conditions. ER activity in regulating target genes is modulated by the binding of both steroidal and synthetic nonsteroidal lig...

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Bibliographische Detailangaben
Hauptverfasser: Paulmurugan, Ramasamy, Tamrazi, Anobel, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Gambhir, Sanjiv S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Endocrine Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453600/
https://ncbi.nlm.nih.gov/pubmed/18451095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0570
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