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A Human Estrogen Receptor (ER)α Mutation with Differential Responsiveness to Nonsteroidal Ligands: Novel Approaches for Studying Mechanism of ER Action

Estrogens, acting through the estrogen receptors (ERs), play crucial roles in regulating the function of reproductive and other systems under physiological and pathological conditions. ER activity in regulating target genes is modulated by the binding of both steroidal and synthetic nonsteroidal lig...

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Autori principali: Paulmurugan, Ramasamy, Tamrazi, Anobel, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Gambhir, Sanjiv S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453600/
https://ncbi.nlm.nih.gov/pubmed/18451095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0570
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