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A Single-Molecule Nanopore Device Detects DNA Polymerase Activity With Single-Nucleotide Resolution
The ability to monitor DNA polymerase activity with single-nucleotide resolution has been the cornerstone of a number of advanced single-molecule DNA sequencing concepts. Toward this goal, we report the first spatially-resolved observation of DNA polymerase activity with single-base resolution at th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453067/ https://ncbi.nlm.nih.gov/pubmed/18166054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja077082c |
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