Inhibition by quinolones of DNA gyrase from Staphylococcus aureus.

In order to clarify the mechanism of action of quinolones against Staphylococcus aureus, the subunit A and B proteins of DNA gyrase were separately purified from a crude extract of S. aureus FDA 209-P. The reconstituted enzyme exhibited ATP-dependent DNA supercoiling activity. The inhibitory effects...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Tanaka, M, Sato, K, Kimura, Y, Hayakawa, I, Osada, Y, Nishino, T
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1991
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656864/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1489
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