Inhibition by quinolones of DNA gyrase from Staphylococcus aureus.

In order to clarify the mechanism of action of quinolones against Staphylococcus aureus, the subunit A and B proteins of DNA gyrase were separately purified from a crude extract of S. aureus FDA 209-P. The reconstituted enzyme exhibited ATP-dependent DNA supercoiling activity. The inhibitory effects...

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Detaylı Bibliyografya
Asıl Yazarlar: Tanaka, M, Sato, K, Kimura, Y, Hayakawa, I, Osada, Y, Nishino, T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC245197/
https://ncbi.nlm.nih.gov/pubmed/1656864
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