Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

Cytochrome c release and the mitochondrial permeability transition (PT), including loss of the transmembrane potential (Δψ), play an important role in apoptosis. Using isolated mitochondria, we found that recombinant Bax and Bak, proapoptotic members of the Bcl-2 family, induced mitochondrial Δψ los...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Narita, Masashi, Shimizu, Shigeomi, Ito, Toshinori, Chittenden, Thomas, Lutz, Robert J., Matsuda, Hikaru, Tsujimoto, Yoshihide
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9843949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.25.14681
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