Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

Cytochrome c release and the mitochondrial permeability transition (PT), including loss of the transmembrane potential (Δψ), play an important role in apoptosis. Using isolated mitochondria, we found that recombinant Bax and Bak, proapoptotic members of the Bcl-2 family, induced mitochondrial Δψ los...

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Detaylı Bibliyografya
Asıl Yazarlar: Narita, Masashi, Shimizu, Shigeomi, Ito, Toshinori, Chittenden, Thomas, Lutz, Robert J., Matsuda, Hikaru, Tsujimoto, Yoshihide
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC24509/
https://ncbi.nlm.nih.gov/pubmed/9843949
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