Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

Cytochrome c release and the mitochondrial permeability transition (PT), including loss of the transmembrane potential (Δψ), play an important role in apoptosis. Using isolated mitochondria, we found that recombinant Bax and Bak, proapoptotic members of the Bcl-2 family, induced mitochondrial Δψ los...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Narita, Masashi, Shimizu, Shigeomi, Ito, Toshinori, Chittenden, Thomas, Lutz, Robert J., Matsuda, Hikaru, Tsujimoto, Yoshihide
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9843949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.25.14681
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