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Fractionation factors and activation energies for exchange of the low barrier hydrogen bonding proton in peptidyl trifluoromethyl ketone complexes of chymotrypsin

NMR investigations have been carried out of complexes between bovine chymotrypsin A(α) and a series of four peptidyl trifluoromethyl ketones, listed here in order of increasing affinity for chymotrypsin: N-Acetyl-l-Phe-CF(3), N-Acetyl-Gly-l-Phe-CF(3), N-Acetyl-l-Val-l-Phe-CF(3), and N-Acetyl-l-Leu-l...

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Bibliografske podrobnosti
Main Authors: Lin, Jing, Westler, William M., Cleland, W. Wallace, Markley, John L., Frey, Perry A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC24506/
https://ncbi.nlm.nih.gov/pubmed/9843946
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