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The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis

Apoptotic cells must be rapidly eliminated to avoid harmful inflammatory and autoimmune reactions. Innate immunity is designed/poised to identify dying cells by their unique surface-associated molecular patterns. Here we demonstrate for the first time, to our knowledge, that the human complement pro...

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Detalhes bibliográficos
Main Authors: Kemper, Claudia, Mitchell, Lynne M., Zhang, Lijuan, Hourcade, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2449358/
https://ncbi.nlm.nih.gov/pubmed/18579773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801015105
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