Anti-Mouse Properdin TSR 5/6 Monoclonal Antibodies Block Complement Alternative Pathway-dependent Pathogenesis

The complement alternative pathway (AP) is a major contributor to a broad and growing spectrum of diseases that includes age-related macular degeneration, atypical hemolytic uremic syndrome, and preeclampsia. As a result, there is much interest in the therapeutic disruption of AP activity. Properdin...

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Dettagli Bibliografici
Pubblicato in:Monoclon Antib Immunodiagn Immunother
Autori principali: Bertram, Paula, Akk, Antonina M., Zhou, Hui-fang, Mitchell, Lynne M., Pham, Christine T.N., Hourcade, Dennis E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350452/
https://ncbi.nlm.nih.gov/pubmed/25723276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2014.0066
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