Genetic dissection of the biosynthetic route to gentamicin A(2) by heterologous expression of its minimal gene set

Since the first use of streptomycin as an effective antibiotic drug in the treatment of tuberculosis, aminoglycoside antibiotics have been widely used against a variety of bacterial infections for over six decades. However, the pathways for aminoglycoside biosynthesis still remain unclear, mainly be...

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Bibliografische gegevens
Hoofdauteurs: Park, Je Won, Hong, Jay Sung Joong, Parajuli, Niranjan, Jung, Won Seok, Park, Sung Ryeol, Lim, Si-Kyu, Sohng, Jae Kyung, Yoon, Yeo Joon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448848/
https://ncbi.nlm.nih.gov/pubmed/18550838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803164105
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