Genetic dissection of the biosynthetic route to gentamicin A(2) by heterologous expression of its minimal gene set

Since the first use of streptomycin as an effective antibiotic drug in the treatment of tuberculosis, aminoglycoside antibiotics have been widely used against a variety of bacterial infections for over six decades. However, the pathways for aminoglycoside biosynthesis still remain unclear, mainly be...

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Bibliografiska uppgifter
Huvudupphovsmän: Park, Je Won, Hong, Jay Sung Joong, Parajuli, Niranjan, Jung, Won Seok, Park, Sung Ryeol, Lim, Si-Kyu, Sohng, Jae Kyung, Yoon, Yeo Joon
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448848/
https://ncbi.nlm.nih.gov/pubmed/18550838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803164105
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