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Genetic dissection of the biosynthetic route to gentamicin A(2) by heterologous expression of its minimal gene set
Since the first use of streptomycin as an effective antibiotic drug in the treatment of tuberculosis, aminoglycoside antibiotics have been widely used against a variety of bacterial infections for over six decades. However, the pathways for aminoglycoside biosynthesis still remain unclear, mainly be...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2448848/ https://ncbi.nlm.nih.gov/pubmed/18550838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803164105 |
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