NK T cells provide lipid antigen-specific cognate help for B cells

The mechanisms of T cell help for production of antilipid antibodies are largely unknown. This study shows that invariant NK T cells (iNK T cells) and B cells cooperate in a model of antilipid antigen-specific antibody responses. We use a model haptenated lipid molecule, 4-hydroxy-3-nitrophenyl-αGal...

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Detalhes bibliográficos
Principais autores: Leadbetter, Elizabeth A., Brigl, Manfred, Illarionov, Petr, Cohen, Nadia, Luteran, Megan C., Pillai, Shiv, Besra, Gurdyal S., Brenner, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448838/
https://ncbi.nlm.nih.gov/pubmed/18550809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801375105
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