Phospholipase D1 is an effector of Rheb in the mTOR pathway

The mammalian target of rapamycin (mTOR) assembles a signaling network essential for the regulation of cell growth, which has emerged as a major target of anticancer therapies. The tuberous sclerosis complex 1 and 2 (TSC1/2) proteins and their target, the small GTPase Rheb, constitute a key regulato...

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Détails bibliographiques
Auteurs principaux: Sun, Y., Fang, Y., Yoon, M.-S., Zhang, C., Roccio, M., Zwartkruis, F. J., Armstrong, M., Brown, H. A., Chen, J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448829/
https://ncbi.nlm.nih.gov/pubmed/18550814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712268105
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