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Nuclear Receptor CAR Requires Early Growth Response 1 to Activate the Human Cytochrome P450 2B6 Gene
The nuclear receptor CAR (constitutive active/androstane receptor) is a drug-sensing transcription factor, regulating the hepatic genes that encode various drug-metabolizing enzymes. We have now characterized the novel regulatory mechanism by which the signal molecule EGR1 (early growth response 1)...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2008
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447624/ https://ncbi.nlm.nih.gov/pubmed/18303024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800729200 |
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