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Site-Specific Release of Nascent Chains from Ribosomes at a Sense Codon

“2A” oligopeptides are autonomous elements containing a D(V/I)EXNPGP motif at the C terminus. Protein synthesis from an open reading frame containing an internal 2A coding sequence yields two separate polypeptides, corresponding to sequences up to and including 2A and those downstream. We show that...

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Detalhes bibliográficos
Main Authors: Doronina, Victoria A., Wu, Cheng, de Felipe, Pablo, Sachs, Matthew S., Ryan, Martin D., Brown, Jeremy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447138/
https://ncbi.nlm.nih.gov/pubmed/18458056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00421-08
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