Quantitative determination of ribosome nascent chain stability

Accurate protein folding is essential for proper cellular and organismal function. In the cell, protein folding is carefully regulated; changes in folding homeostasis (proteostasis) can disrupt many cellular processes and have been implicated in various neurodegenerative diseases and other pathologi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Samelson, Avi J., Jensen, Madeleine K., Soto, Randy A., Cate, Jamie H. D., Marqusee, Susan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127326/
https://ncbi.nlm.nih.gov/pubmed/27821780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610272113
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