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Analysis of Type II Secretion of Recombinant Pneumococcal PspA and PspC in a Salmonella enterica Serovar Typhimurium Vaccine with Regulated Delayed Antigen Synthesis

Recombinant attenuated Salmonella vaccines (RASVs) have been used extensively to express and deliver heterologous antigens to host mucosal tissues. Immune responses can be enhanced greatly when the antigen is secreted to the periplasm or extracellular compartment. The most common method for accompli...

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Main Authors: Xin, Wei, Wanda, Soo-Young, Li, Yuhua, Wang, Shifeng, Mo, Hua, Curtiss, Roy
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446722/
https://ncbi.nlm.nih.gov/pubmed/18458067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01623-07
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