Salmonella enterica Serovar Typhimurium Strains with Regulated Delayed Attenuation In Vivo

Recombinant bacterial vaccines must be fully attenuated for animal or human hosts to avoid inducing disease symptoms while exhibiting a high degree of immunogenicity. Unfortunately, many well-studied means for attenuating Salmonella render strains more susceptible to host defense stresses encountere...

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Detalhes bibliográficos
Main Authors: Curtiss, Roy, Wanda, Soo-Young, Gunn, Bronwyn M., Zhang, Xin, Tinge, Steven A., Ananthnarayan, Vidya, Mo, Hua, Wang, Shifeng, Kong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643627/
https://ncbi.nlm.nih.gov/pubmed/19103774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00693-08
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