Construction of Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Vector Strains for Safety in Newborn and Infant Mice

Recombinant bacterial vaccines must be safe, efficacious, and well tolerated, especially when administered to newborns and infants to prevent diseases of early childhood. Many means of attenuation have been shown to render vaccine strains susceptible to host defenses or unable to colonize lymphoid t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gunn, Bronwyn M., Wanda, Soo-Young, Burshell, Dana, Wang, Caihong, Curtiss, Roy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Vaccine Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837962/
https://ncbi.nlm.nih.gov/pubmed/20053874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00412-09
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