Construction of Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Vector Strains for Safety in Newborn and Infant Mice

Recombinant bacterial vaccines must be safe, efficacious, and well tolerated, especially when administered to newborns and infants to prevent diseases of early childhood. Many means of attenuation have been shown to render vaccine strains susceptible to host defenses or unable to colonize lymphoid t...

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Bibliografiske detaljer
Main Authors: Gunn, Bronwyn M., Wanda, Soo-Young, Burshell, Dana, Wang, Caihong, Curtiss, Roy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Vaccine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837962/
https://ncbi.nlm.nih.gov/pubmed/20053874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00412-09
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