Immunization with Salmonella enterica Serovar Typhimurium-Derived Outer Membrane Vesicles Delivering the Pneumococcal Protein PspA Confers Protection against Challenge with Streptococcus pneumoniae

Gram-negative bacteria produce outer membrane vesicles (OMVs) that serve a variety of functions related to survival and pathogenicity. Periplasmic and outer membrane proteins are naturally captured during vesicle formation. This property has been exploited as a method to derive immunogenic vesicle p...

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Bibliografiske detaljer
Main Authors: Muralinath, Maneesha, Kuehn, Meta J., Roland, Kenneth L., Curtiss, Roy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028854/
https://ncbi.nlm.nih.gov/pubmed/21115718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00950-10
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