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PspA Family Fusion Proteins Delivered by Attenuated Salmonella enterica Serovar Typhimurium Extend and Enhance Protection against Streptococcus pneumoniae

Pneumococcal surface protein A (PspA) is highly immunogenic and can induce a protective immune response against pneumococcal infection. PspA is divided into two major families based on serological variability: family 1 and family 2. To provide broad protection, PspA proteins from pneumococcal strain...

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Detalhes bibliográficos
Main Authors: Xin, Wei, Li, Yuhua, Mo, Hua, Roland, Kenneth L., Curtiss, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747926/
https://ncbi.nlm.nih.gov/pubmed/19687204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00486-09
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