Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism

Cystic fibrosis (CF) is associated with fatty acid alterations characterized by low linoleic and docosahexaenoic acid. It is not clear whether these fatty acid alterations are directly linked to cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction or result from nutrient malabsorpt...

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Autores principales: Andersson, Charlotte, Al-Turkmani, M. Rabie, Savaille, Juanito E., Alturkmani, Ragheed, Katrangi, Waddah, Cluette-Brown, Joanne E., Zaman, Munir M., Laposata, Michael, Freedman, Steven D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2444007/
https://ncbi.nlm.nih.gov/pubmed/18441018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M700388-JLR200
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