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Increased Elongase 6 and Δ9-Desaturase Activity are Associated with n-7 and n-9 Fatty Acid Changes in Cystic Fibrosis

Patients with cystic fibrosis, caused by mutations in CFTR, exhibit specific and consistent alterations in the levels of particular unsaturated fatty acids compared with healthy controls. Evidence suggests that these changes may play a role in the pathogenesis of this disease. Among these abnormalit...

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Detalhes bibliográficos
Main Authors: Thomsen, Kelly F., Laposata, Michael, Njoroge, Sarah W., Umunakwe, Obi C., Katrangi, Waddah, Seegmiller, Adam C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711213/
https://ncbi.nlm.nih.gov/pubmed/21544602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-011-3563-z
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