DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity

Patients and models of cystic fibrosis (CF) exhibit consistent abnormalities of polyunsaturated fatty acid composition, including decreased linoleate (LA) and docosahexaenoate (DHA) and variably increased arachidonate (AA), related in part to increased expression and activity of fatty acid desaturas...

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Detalhes bibliográficos
Main Authors: Njoroge, Sarah W., Laposata, Michael, Katrangi, Waddah, Seegmiller, Adam C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269161/
https://ncbi.nlm.nih.gov/pubmed/22095831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M018101
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