Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr(−/−) transgenic mice

Cystic fibrosis (CF) patients display a fatty acid imbalance characterized by low linoleic acid levels and variable changes in arachidonic acid. This led to the recommendation that CF patients consume a high-fat diet containing >6% linoleic acid. We hypothesized that increased conversion of linol...

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Detalhes bibliográficos
Main Authors: Zaman, Munir M., Martin, Camilia R., Andersson, Charlotte, Bhutta, Abdul Q., Cluette-Brown, Joanne E., Laposata, Michael, Freedman, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980390/
https://ncbi.nlm.nih.gov/pubmed/20656894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00346.2009
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