Evaluating the Effects of Imputation on the Power, Coverage, and Cost Efficiency of Genome-wide SNP Platforms

Genotype imputation is potentially a zero-cost method for bridging gaps in coverage and power between genotyping platforms. Here, we quantify these gains in power and coverage by using 1,376 population controls that are from the 1958 British Birth Cohort and were genotyped by the Wellcome Trust Case...

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Detaylı Bibliyografya
Asıl Yazarlar: Anderson, Carl A., Pettersson, Fredrik H., Barrett, Jeffrey C., Zhuang, Joanna J., Ragoussis, Jiannis, Cardon, Lon R., Morris, Andrew P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2008
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443836/
https://ncbi.nlm.nih.gov/pubmed/18589396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.06.008
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