Optimizing the Power of Genome-Wide Association Studies by Using Publicly Available Reference Samples to Expand the Control Group

Genome-wide association (GWA) studies have proved extremely successful in identifying novel genetic loci contributing effects to complex human diseases. In doing so, they have highlighted the fact that many potential loci of modest effect remain undetected, partly due to the need for samples consist...

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Detalhes bibliográficos
Main Authors: Zhuang, Joanna J, Zondervan, Krina, Nyberg, Fredrik, Harbron, Chris, Jawaid, Ansar, Cardon, Lon R, Barratt, Bryan J, Morris, Andrew P
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962805/
https://ncbi.nlm.nih.gov/pubmed/20088020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20482
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