Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

High coverage whole genome sequencing provides near complete information about genetic variation. However, other technologies can be more efficient in some settings by (a) reducing redundant coverage within samples and (b) exploiting patterns of genetic variation across samples. To characterize as m...

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Dades bibliogràfiques
Autors principals: Flannick, Jason, Korn, Joshua M., Fontanillas, Pierre, Grant, George B., Banks, Eric, Depristo, Mark A., Altshuler, David
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395607/
https://ncbi.nlm.nih.gov/pubmed/22807667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002604
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