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Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

High coverage whole genome sequencing provides near complete information about genetic variation. However, other technologies can be more efficient in some settings by (a) reducing redundant coverage within samples and (b) exploiting patterns of genetic variation across samples. To characterize as m...

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Hlavní autoři: Flannick, Jason, Korn, Joshua M., Fontanillas, Pierre, Grant, George B., Banks, Eric, Depristo, Mark A., Altshuler, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395607/
https://ncbi.nlm.nih.gov/pubmed/22807667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002604
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