A carregar...
Expression of expanded polyglutamine targets profilin for degradation and alters actin dynamics
Huntington’s disease is caused by polyglutamine expansion in the huntingtin protein. Huntingtin directly interacts with profilin, a major actin monomer sequestering protein and a key integrator of signals leading to actin polymerization. We observed a progressive loss of profilin in the cerebral cor...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442575/ https://ncbi.nlm.nih.gov/pubmed/18417352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.02.007 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|