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A Protective Role for the Human SMG-1 Kinase against Tumor Necrosis Factor-α-induced Apoptosis
The human suppressor of morphogenesis in genitalia-1 (hSMG-1) protein kinase plays dual roles in mRNA surveillance and genotoxic stress response pathways in human cells. Here, we report that small interfering RNA-mediated depletion of hSMG-1, but not ATM, ATR, hUpf1, or hUpf2, in human U2OS osteosar...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442360/ https://ncbi.nlm.nih.gov/pubmed/18326048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708008200 |
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