Lysosomal Serine Protease CLN2 Regulates Tumor Necrosis Factor-α-mediated Apoptosis in a Bid-dependent Manner

Apoptosis is a highly organized, energy-dependent program by which multicellular organisms eliminate damaged, superfluous, and potentially harmful cells. Although caspases are the most prominent group of proteases involved in the apoptotic process, the role of lysosomes has only recently been unmask...

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Detalhes bibliográficos
Main Authors: Autefage, Hélène, Albinet, Virginie, Garcia, Virginie, Berges, Hortense, Nicolau, Marie-Laure, Therville, Nicole, Altié, Marie-Françoise, Caillaud, Catherine, Levade, Thierry, Andrieu-Abadie, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670156/
https://ncbi.nlm.nih.gov/pubmed/19246452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807151200
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