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Cue1p Is an Activator of Ubc7p E2 Activity in Vitro and in Vivo
Ubc7p is a ubiquitin-conjugating enzyme (E2) that functions with endoplasmic reticulum (ER)-resident ubiquitin ligases (E3s) to promote endoplasmic reticulum-associated degradation (ERAD). Ubc7p only functions in ERAD if bound to the ER surface by Cue1p, a membrane-anchored ER protein. The role of C...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442330/ https://ncbi.nlm.nih.gov/pubmed/18321851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801122200 |
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