Expression of Angiotensin-converting Enzyme Changes Major Histocompatibility Complex Class I Peptide Presentation by Modifying C Termini of Peptide Precursors

We recently reported a mouse model called ACE 10/10 in which macrophages overexpress the carboxypeptidase angiotensin-converting enzyme (ACE). These mice have an enhanced inflammatory response to tumors that markedly inhibits tumor growth. Here, we show that ACE modifies the C termini of peptides fo...

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Xehetasun bibliografikoak
Egile Nagusiak: Shen, Xiao Z., Lukacher, Aron E., Billet, Sandrine, Williams, Ifor R., Bernstein, Kenneth E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Enzyme Catalysis and Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442301/
https://ncbi.nlm.nih.gov/pubmed/18252713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709574200
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