Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme

Amyloid β-protein 1–42 (Aβ42) is believed to play a causative role in the development of Alzheimer disease (AD), although it is a minor part of Aβ. In contrast, Aβ40 is the predominant secreted form of Aβ and recent studies have suggested that Aβ40 has neuroprotective effects and inhibits amyloid de...

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Detalhes bibliográficos
Main Authors: Zou, Kun, Maeda, Tomoji, Watanabe, Atsushi, Liu, Junjun, Liu, Shuyu, Oba, Ryutaro, Satoh, Yoh-ichi, Komano, Hiroto, Michikawa, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797262/
https://ncbi.nlm.nih.gov/pubmed/19773553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011437
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