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Mitochondrial DNA Damage and Repair in Neurodegenerative Disorders
By producing ATP and regulating intracellular calcium levels, mitochondria are vital for the function and survival of neurons. Oxidative stress and damage to mitochondrial DNA during the aging process can impair mitochondrial energy metabolism and ion homeostasis in neurons, thereby rendering them v...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442166/ https://ncbi.nlm.nih.gov/pubmed/18463003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.012 |
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