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Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers

Variation in penetrance estimates for BRCA1/2 carriers suggests that other environmental and genetic factors may modify cancer risk in carriers. The GSTM1, T1 and P1 isoenzymes are involved in metabolism of environmental carcinogens. The GSTM1 and GSTT1 gene is absent in a substantial proportion of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kadouri, L, Kote-Jarai, Z, Hubert, A, Baras, M, Abeliovich, D, Hamburger, T, Peretz, T, Eeles, R A
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441947/
https://ncbi.nlm.nih.gov/pubmed/18542066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604394
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