Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype

There is a high and rising prevalence of prostate cancer (PRCA) within the male population of the United Kingdom. Although the relative risk of PRCA is higher in male BRCA2 and BRCA1 mutation carriers, the histological characteristics of this malignancy in these groups have not been clearly defined....

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Библиографические подробности
Главные авторы: Mitra, A, Fisher, C, Foster, C S, Jameson, C, Barbachanno, Y, Bartlett, J, Bancroft, E, Doherty, R, Kote-Jarai, Z, Peock, S, Easton, D, Eeles, R
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2008
Предметы:
Genetics and Genomics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361443/
https://ncbi.nlm.nih.gov/pubmed/18182994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604132
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