Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype

There is a high and rising prevalence of prostate cancer (PRCA) within the male population of the United Kingdom. Although the relative risk of PRCA is higher in male BRCA2 and BRCA1 mutation carriers, the histological characteristics of this malignancy in these groups have not been clearly defined....

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Detalhes bibliográficos
Main Authors: Mitra, A, Fisher, C, Foster, C S, Jameson, C, Barbachanno, Y, Bartlett, J, Bancroft, E, Doherty, R, Kote-Jarai, Z, Peock, S, Easton, D, Eeles, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361443/
https://ncbi.nlm.nih.gov/pubmed/18182994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604132
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