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Generation and characterization of transgenic mice expressing a T-cell receptor specific for the tumour-associated antigen MDM2

T-cell-based antigen-specific immunotherapy targeting tumour-associated antigens offers the potential for cancer immunotherapy. However, the majority of identified tumour-associated antigens are also expressed at low levels in normal tissues and mechanisms of tolerance induction are likely to affect...

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Autori principali: Xue, Shao-An, Bendle, Gavin M, Holler, Angelika, Stauss, Hans J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440825/
https://ncbi.nlm.nih.gov/pubmed/18217949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02793.x
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