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A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection

Adoptive transfer of antigen-specific CD4(+) and CD8(+) T cells is one of the most efficient forms of cancer immunotherapy. However, the isolation of antigen-specific CD4(+) T cells is limited because only few tumor-associated helper epitopes are identified. Here, we used T cell antigen receptor gen...

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Detalhes bibliográficos
Main Authors: Morris, Emma C., Tsallios, Aristotle, Bendle, Gavin M., Xue, Shao-an, Stauss, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142362/
https://ncbi.nlm.nih.gov/pubmed/15908507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500357102
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