Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus

Ebolavirus causes highly lethal hemorrhagic fever in humans. The envelope-displayed viral glycoprotein (GP) is the primary target of humoral immunity induced by natural exposure and vaccination. No T cell epitopes in the GP have been characterized in humans. A phase I clinical trial of a heterologou...

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Publicado en:Cell Rep
Main Authors: Powlson, Jonathan, Wright, Daniel, Zeltina, Antra, Giza, Mark, Nielsen, Morten, Rampling, Tommy, Venkatrakaman, Navin, Bowden, Thomas A., Hill, Adrian V.S., Ewer, Katie J.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899439/
https://ncbi.nlm.nih.gov/pubmed/31775024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.105
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