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Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks

Background: Several monoclonal antibodies (mAb) are being evaluated as treatment options for the current 2014 Ebola outbreak. But they were derived from and tested for protection against the older 1976 Mayinga or 1995 Kikwit Zaire Ebolaviruses (EBOV). The EBOV sequences reported for the current outb...

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Detalhes bibliográficos
Publicado no:PLoS Curr
Main Authors: Ponomarenko, Julia, Vaughan, Kerrie, Sette, Alessandro, Maurer-Stroh, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234462/
https://ncbi.nlm.nih.gov/pubmed/25642381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.outbreaks.f1a7028a13ce1c5f0bdbb4b0cc0b919b
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