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Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks

Background: Several monoclonal antibodies (mAb) are being evaluated as treatment options for the current 2014 Ebola outbreak. But they were derived from and tested for protection against the older 1976 Mayinga or 1995 Kikwit Zaire Ebolaviruses (EBOV). The EBOV sequences reported for the current outb...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Curr
Hauptverfasser: Ponomarenko, Julia, Vaughan, Kerrie, Sette, Alessandro, Maurer-Stroh, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234462/
https://ncbi.nlm.nih.gov/pubmed/25642381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.outbreaks.f1a7028a13ce1c5f0bdbb4b0cc0b919b
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